The Problem
Cryopreservation remains one of the biggest bottlenecks in regenerative medicine and cell and gene therapies. Conventional methods lack consistency and may destroy about half of every sample, wasting time, money, and material.
Our solution
FreezOpt™ is a non-chemical ice nucleation “seed” designed to protect cells during freezing and thawing and has been shown to nearly
double cell recovery and better preserve cell function vs conventional methods.
ABOUT & PARTNERSHIPS
Transforming Cell Preservation
HOHCells is advancing the science of cryopreservation to enable more reliable, scalable, and cost effective cell based research. Our mission is simple: protect living cells through the freeze–thaw cycle so they remain intact and functional for discovery and development.
About us
Our Leadership Team
HOHCells’ technology is based on breakthrough research at the He Research Group’s Multiscale Biomaterials Engineering (MBE) Laboratory at the University of Maryland. The company holds a granted U.S. patent and multiple pending applications covering diverse technologies related to tools and methods to enhance and enable cell-based research and therapy.
Supported by the Maryland Stem Cell Research Fund with pilot manufacturing facilities housed at Mtech Ventures in College Park, Maryland, HOHCells is an emerging leader in stem cell research products.
Dr. Xiaoming (Shawn) He
Founder
Internationally recognized cryobiologist and inventor whose research and patented technologies underpin HOHCells’ next- generation cryopreservation platform.
Greg Merril
CEO
Experienced life science executive focused on building and commercializing differentiated platforms for advanced biological research.
Bryce Walker
Director of Manufacturing
Manufacturing and operations leader specializing in process development, scale-up, and quality system design for advanced biological technologies.
Partnerships
We collaborate with research institutions, CDMOs, and biotech manufacturers to integrate next-generation cryopreservation into real-world cell research.
Partnership opportunities include:
- Validation studies and joint publications
- OEM and licensing agreements
- Distribution partnerships
- Custom development for specific cell types
Ready to double your cell recovery?
Join leading research institutions and biotech companies using FreezOpt to advance cell research development.